Science Journal of Medicine and Clinical Trials
May 2012,Volume 2012, ISSN: 2276-7487
© Author(s) 2012. This work is distributed under the Creative Commons Attribution 3.0 License.
Research Article
Laryngopharyngeal Reflux- A New Paradigm of Airway Disease
Prof. Kamrul Hassan Tarafder1, Prof. Pran Gopal Datta2, Prof. Abu Shafi Ahmed Amin1, Prof. M. Alamgir Chowdhury3, Dr. Ahmed Tariq4, Dr. Partho Protim Das5
1Professor, Otolaryngology - Head & Neck Surgery, BSMMU, Dhaka, Bangladesh.
2Vice Chancellor, BSMMU, Dhaka, Bangladesh.
3Professor, Otolaryngology - Head & Neck Surgery, Anwer Khan Modern Medical College, Dhanmondi, Dhaka, Bangladesh.
4Medical Officer, deputed to BSMMU, Dhaka, Bangladesh.
5Assistant Professor, Medicine, Dhaka Medical College & Hospital, Dhaka, Bangladesh.
Accepted 12 April 2012; Available Online 4 May, 2012
doi: 10.7237/sjmct/138
Abstract:
Laryngopharyngeal reflux, an extra-esophageal variation of gastroesophageal reflux disease (GER, GERD, and LRP) is believed to be an important etiologic factor in the development of many inflammatory and neoplastic disorders of the upper aerodigestive tract. It has been associated with laryngeal symptoms of dysphonia, globus sensation, excessive throat-clearing and chronic cough in children as well as in adults. This article reviews the effects, current diagnostic techniques and treatment of reflux. For proper evaluation of reflux patients two scoring system developed by Belafsky et al in 2002, Reflux Finding Score (RFS) gauzes the laryngoscopic changes caused by reflux laryngitis. Reflux Symptom Index (RSI) is a preset questionnaire answered by the patient himself to find out the severity of LPR. Effective medical treatment has been claimed to reverse the reflux findings score which can be reliably monitored by 24 hour dual probe pH study. Emergence of newer PPIs has got promising results in the treatment of LPR without need for any surgical intervention.
Keyword: Antioxidant, Diabetes, blood glucose, Alloxan, Citrus maxima